Kiss-Me-Over-the-Garden-Gate thrives in consistently moist soil. Water regularly, especially during dry spells, ensuring the soil does not dry out completely. Aim for deep watering to encourage strong root development. Reduce frequency slightly in cooler weather or if grown in partial shade, but always keep the soil from becoming parched.

Pruning is generally minimal for Kiss-Me-Over-the-Garden-Gate. Deadheading spent flower spikes can encourage a tidier appearance and may promote a longer blooming period, though it's often allowed to self-seed. Pinching back young plants can encourage bushier growth, but its natural habit is upright and somewhat sprawling.

This plant is easily propagated by seed. Sow seeds directly outdoors in spring after the last frost, or start them indoors 4-6 weeks earlier. Seeds often require light for germination, so sow them shallowly. It readily self-seeds, so volunteer seedlings may appear in subsequent years, making propagation quite effortless.

As an annual, Kiss-Me-Over-the-Garden-Gate does not require repotting in the traditional sense. If starting seeds indoors, transplant seedlings into larger pots once they have a few true leaves before moving them to their final outdoor location. Ensure the final container is adequately sized to accommodate its mature height and spread.