Water Euphorbia tirucalli deeply but infrequently, allowing the soil to dry out completely between waterings. Overwatering is a common cause of root rot. During winter or cooler periods, reduce watering significantly, perhaps once a month or less, depending on ambient temperatures and humidity. Ensure good drainage to prevent waterlogging.

Pruning is primarily done to maintain shape, control size, or remove damaged/diseased stems. Always wear protective gloves and eye protection when pruning due to the irritating milky sap. Cuttings can be taken for propagation. Prune in late spring or early summer for best results, allowing cuts to callus before propagation.

Euphorbia tirucalli is easily propagated from stem cuttings. Take cuttings 10-15 cm long, allow the cut end to callus for several days in a dry, shaded area to stop the sap flow. Once callused, plant the cuttings in well-draining succulent mix. Keep the soil slightly moist until roots develop, which can take a few weeks. Provide warmth and bright indirect light.

Repotting is generally needed every 2-3 years or when the plant becomes root-bound. Choose a pot only slightly larger than the previous one, ensuring it has excellent drainage. Use a fresh, well-draining succulent or cactus potting mix. Repot during the active growing season (spring or early summer). Wear protective gear to handle the plant and its sap during repotting.